Most of the anti-phage defense systems of bacteria can be described as a combination of two main components.
Most of the anti-phage defense systems of bacteria can be described as a combination of two main components.
First, a sensing component that detects phage infection to trigger the immune response
First, a sensing component that detects phage infection to trigger the immune response
(see [defense-systems_trigger](/general-concepts/defense-systems_trigger/)).
(see [defense-systems_trigger](/general-concepts/defense-systems_trigger)).
Second, an effector component that mediates the immune response following the detection of phage infection.
Second, an effector component that mediates the immune response following the detection of phage infection.
The effector components of anti-phage systems are very diverse, and can be arbitrarily distributed in broad categories :ref{doi=10.1038/s41579-023-00934-x} :
The effector components of anti-phage systems are very diverse, and can be arbitrarily distributed in broad categories :ref{doi=10.1038/s41579-023-00934-x} :