Merge branch 'main' into dev

content/3.defense-systems/rst_tir-nlr.md

@@ -10,9 +10,24 @@ tableColumns:
     Activator: Unknown
     Effector: Unknown
     PFAM: PF13676
+contributors: 
+  - Lucas Paoli
+relevantAbstracts:
+  - doi: 10.1016/j.chom.2022.02.018
 ---
 
 # Rst_TIR-NLR
+
+## Description
+
+The Rst_TIR-NLR system is named after the first author of the paper describing it (Rousset et al. 2022) and the domains of the only protein it contains (TIR, toll-interleukin-1 receptor, and NLR, nucleotide-binding leucine rich repeat receptor) :ref{doi=10.1016/j.chom.2022.02.018}.
+
+This system is very similar to other bacterial defense systems: bNACHT (https://defense-finder.pasteur.cloud/wiki/defense-systems/nlr), CARD_NLR (https://defense-finder.pasteur.cloud/wiki/defense-systems/card_nlr), Avs (AVAST) (https://defense-finder.pasteur.cloud/wiki/defense-systems/avs). 
+
+## Molecular mechanisms
+
+As far as we are aware, the molecular mechanism is unknown. However, the molecular mechanism of closely related systems was previously studied. See bNACHT (https://defense-finder.pasteur.cloud/wiki/defense-systems/nlr), CARD_NLR (https://defense-finder.pasteur.cloud/wiki/defense-systems/card_nlr) and Avs (AVAST) (https://defense-finder.pasteur.cloud/wiki/defense-systems/avs)
+
 ## Example of genomic structure
 
 The Rst_TIR-NLR is composed of 1 protein: TIR.
@@ -74,13 +89,3 @@ end
     style Title3 fill:none,stroke:none,stroke-width:none
     style Title4 fill:none,stroke:none,stroke-width:none
 </mermaid>
-## Relevant abstracts
-
-::relevant-abstracts
----
-items:
-    - doi: 10.1016/j.chom.2022.02.018
-
----
-::
-