Update charlie_gp32.md

content/3.defense-systems/charlie_gp32.md

@@ -6,11 +6,27 @@ tableColumns:
       doi: 10.1038/nmicrobiol.2016.251
       abstract: |
         Temperate phages are common, and prophages are abundant residents of sequenced bacterial genomes. Mycobacteriophages are viruses that infect mycobacterial hosts including Mycobacterium tuberculosis and Mycobacterium smegmatis, encompass substantial genetic diversity and are commonly temperate. Characterization of ten Cluster N temperate mycobacteriophages revealed at least five distinct prophage-expressed viral defence systems that interfere with the infection of lytic and temperate phages that are either closely related (homotypic defence) or unrelated (heterotypic defence) to the prophage. Target specificity is unpredictable, ranging from a single target phage to one-third of those tested. The defence systems include a single-subunit restriction system, a heterotypic exclusion system and a predicted (p)ppGpp synthetase, which blocks lytic phage growth, promotes bacterial survival and enables efficient lysogeny. The predicted (p)ppGpp synthetase coded by the Phrann prophage defends against phage Tweety infection, but Tweety codes for a tetrapeptide repeat protein, gp54, which acts as a highly effective counter-defence system. Prophage-mediated viral defence offers an efficient mechanism for bacterial success in host-virus dynamics, and counter-defence promotes phage co-evolution.
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+    Sensor: Unknow
+    Activator: Unknow
+    Effector: Nucleid acid degrading
+contributors: 
+    Rachel Lavenir
+relevantAbstracts:
+    - doi: 10.1038/nmicrobiol.2016.251
+
+
 
 # Charlie_gp32
 
-## To do 
+## Description
+Charlie_gp32 is a small 121-residue putative membrane protein in the bacteriophage charlie and contains a single transmembranaire domain near the N-terminus.
+
+## Molecular mechanisms
+its role in defending against phage Che9c.
+
+## Example of genomic content
+To do
+
 
 ## Structure
 
@@ -47,11 +63,4 @@ end
     style Title3 fill:none,stroke:none,stroke-width:none
     style Title4 fill:none,stroke:none,stroke-width:none
 </mermaid>
-## Relevant abstract
-::relevant-abstracts
----
-items:
-    - doi: 10.1038/nmicrobiol.2016.251
 
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-::