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Merged Nathalie Bechon requested to merge bechon27-main-patch-07171 into main
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Activator: Unknown
Effector: Unknown
PFAM: PF02086
contributors:
- Nathalie Bechon
relevantAbstracts:
- doi: 10.1038/s41564-022-01219-4
---
# PD-Lambda-5
##Description
PD-lambda-5 is a two-gene system identified in a P2-like prophage. It encodes a protein with a nuclease and a HEPN domain, and a predicted methyltransferase. It confers broad anti-phage defense and does not seem to mediate abortive infection.
##Molecular mechanism
PD-lambda-5 molecular mechanism has not been described to date. It confers protection against a broad range of phages, and does not seem to be an abortive infection system.
## Example of genomic structure
The PD-Lambda-5 system is composed of 2 proteins: PD-Lambda-5_A and, PD-Lambda-5_B.
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</mermaid>
## Relevant abstracts
::relevant-abstracts
---
items:
- doi: 10.1038/s41564-022-01219-4
---
::
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