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@@ -32,8 +32,8 @@ This system is composed of 4 genes: JetA, JetB, JetC and JetD. JetA, JetB and Je
The anti-plasmid activity of Wadjet was shown to be a DNA cleaving mechanism specific to close circular DNA :ref{doi=10.1098/rstb.2004.1606}.
The JetABC complex will act as a sensor detecting the foreign DNA using topology sensing.
JetD protein is a homodimeric endonuclease that cleaves double stranded DNA.
JetD need to be in contact with the JetABC complex to be able to cleave DNA.
JetD protein is a homodimeric endonuclease that cleaves double-stranded DNA.
JetD needs to be in contact with the JetABC complex to be able to cleave DNA.
The mechanism suggested by :ref{doi=10.1098/rstb.2004.1606} is that the complex will bind to the DNA and will extrude loops similarly to Muk and other SMC proteins :ref{doi=10.1126/science.abm4012,10.1126/science.abb0981} that will then be cleave by JetD.
@@ -70,7 +70,7 @@ Proportion of genome encoding the Wadjet system for the 14 phyla with more than
## Structure
### Experimentaly determined structure
### Experimentally determined structure
From :ref{doi=10.1098/rstb.2004.1606} in *Pseudomonas aeruginosa* PA14:
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