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Sensor: Unknown
Sensor: Unknown
Activator: Unknown
Activator: Unknown
Effector: Membrane disrupting
Effector: Membrane disrupting
 
contributors:
 
- Florian Tesson
relevantAbstracts:
relevantAbstracts:
- doi: 10.1023/A:1002027321171
- doi: 10.1023/A:1002027321171
- doi: 10.1128/JB.00904-06
- doi: 10.1128/JB.00904-06
---
---
# AbiZ
# AbiZ
 
 
## Description
 
 
AbiZ was discovered in 2006 on a *Lactococcus lactis* conjugative plasmid pTR2030 :ref{doi=10.1128/JB.00904-06}.
 
 
AbiZ is one of the so-called "Abi" systems for "Abortive infection" discovered in the 90's in research related to the dairy industry :ref{doi=10.1016/j.mib.2005.06.006}. AbiZ is classified as abortive infection in :ref{doi=10.1016/j.mib.2023.102312}.
 
 
AbiZ is composed of a single protein AbiZ.
 
 
## Molecular mechanism
 
AbiZ acts as an abortive infection system. AbiZ proteins sense holins and lysins from the infecting bacteriophage and use them to induce premature cell lysis :ref{doi=10.1128/JB.00904-06,10.1146/annurev-virology-011620-040628}.
 
## Example of genomic structure
## Example of genomic structure
The AbiZ is composed of 1 protein: AbiZ.
The AbiZ is composed of 1 protein: AbiZ.
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