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Merged ftesson requested to merge ftesson_abia_good into main
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@@ -10,6 +10,8 @@ tableColumns:
Activator: Unknown
Effector: Unknown
PFAM: PF00078, PF18160, PF18732
contributors:
- Florian Tesson
relevantAbstracts:
- doi: 10.1023/A:1002027321171
- doi: 10.1016/j.mib.2005.06.006
@@ -17,6 +19,19 @@ relevantAbstracts:
---
# AbiA
The AbiA defense system was discovered in 1990 in a lactococcal plasmid :ref{doi=10.1128/aem.56.7.2255-2258.1990}.
AbiA is one of the so-called "Abi" systems for "Abortive infection" discovered in the 90's in research related to the dairy industry :ref{doi=10.1016/j.mib.2005.06.006}. AbiA is classified as a possible abortive infection in :ref{doi=10.1016/j.mib.2023.102312}.
Since it was discovered a similarity in amino acids was found with [AbiK](/defense-systems/abik).
However, with the discovery of dozens of new systems, it was categorized as one of the UG/Abi defense systems :ref{doi=10.1093/nar/gkac467} along with [DRT](/defense-systems/drt) different subsystems, [Abik](/defense-systems/abik), [AbiP2](/defense-systems/abip2) and [Rst_RT_Nitralase_TM](/defense-systems/rst_rt-nitrilase-tm).
Those systems are characterized by the presence of a reverse transcriptase domain of the "Unknown Group RT".
## Molecular mechanism
To our knowledge, the molecular mechanism is unknown. Similarly, for the other systems of this family, the molecular mechanism remains unknown.
## Example of genomic structure
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