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@@ -9,9 +9,22 @@ tableColumns:
Sensor: Unknown
Activator: Unknown
Effector: Unknown
contributors:
- Ernest Mordret
relevant abstracts:
- doi: 10.1038/s41564-022-01219-4
---
# PD-T4-3
## Description
PD-T4-3 is a single gene system isolated during an experimental screen of fosmids derived from 71 strains of diverse E.coli, and cloned back in a derivative of K12. Fragments containing the PD-T4-3 gene were shown to provide resistance to phage T4. The protein is characterized by a GIY-YIG nuclease domain, and mutations inactivating this domain abolished the resistance phenotype. It was originally found on a µ-like prophage
## Molecular mechanism
the molecular mechanism of this system is unknown
## Example of genomic structure
The PD-T4-3 system is composed of one protein: PD-T4-3.
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style Title3 fill:none,stroke:none,stroke-width:none
style Title4 fill:none,stroke:none,stroke-width:none
</mermaid>
## Relevant abstracts
::relevant-abstracts
---
items:
- doi: 10.1038/s41564-022-01219-4
---
::
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