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Commit faf851f4 authored by Cyril  NERIN's avatar Cyril NERIN
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FEAT #96

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...@@ -106,10 +106,26 @@ Creation of the JASS inittable ...@@ -106,10 +106,26 @@ Creation of the JASS inittable
Once, GWAS summary statistics are harmonized, they are integrated into Once, GWAS summary statistics are harmonized, they are integrated into
one file by the using jass command (see detail in command line usage) one file by the using jass command (see detail in command line usage)
``` .. code-block:: shell
jass create-inittable --input-data-path '$GWAS_files_glob_pattern' --init-covariance-path $path_to_covariance_file --regions-map-path $path_to_LD_regions --description-file-path $path_to_gwas_meta_data.csv --init-table-path $path_to_output_inittable
jass create-inittable --input-data-path '$GWAS_files_glob_pattern' --init-covariance-path $path_to_covariance_file --regions-map-path $path_to_LD_regions --description-file-path $path_to_gwas_meta_data.csv --init-table-path $path_to_output_inittable
Add genes and exons annotation to initTable (optional)
------------------------------------------------------
If you want to avoid a (non-blocking) error in the JASS web interface when performing a local analysis on a region of the genome,
you must add the genes and exons to the InitTable
To do this, you need to download the file: RefSeq Reference Genome Annotation GRCh37 from the website: https://www.ncbi.nlm.nih.gov/genome/guide/human/
before unzipping it on your computer and saving it in the JASS_DATA_DIR folder. Then you can run in a terminal the following command:
.. code-block:: shell
jass add-gene-annotation --gene-data-path GRCh37_latest_genomic.gff --init-table-path $path_to_initTable.hdf5 --gene-csv-path df_gene.csv --exon-csv-path df_exon.csv
``` .. warning::
For this command, it is necessary to specify the full path of initTable.hdf5 even if this file is in the JASS_DATA_DIR folder. You can use the environment variable $JASS_DATA_DIR (Linux) or %JASS_DATA_DIR% (Windows)
The advantage of adding genes and exons in the initTable is to have an additional graph in the web page of the results of the local analysis:
the position of genes and exons in the studied genomic region (see paragraph: **web usage, section B - Analysis by region**)
.. bibliography:: reference.bib .. bibliography:: reference.bib
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