Update pd-t7-1.md

content/3.defense-systems/pd-t7-1.md

@@ -6,12 +6,20 @@ tableColumns:
       doi: 10.1038/s41564-022-01219-4
       abstract: |
         The ancient, ongoing coevolutionary battle between bacteria and their viruses, bacteriophages, has given rise to sophisticated immune systems including restriction-modification and CRISPR-Cas. Many additional anti-phage systems have been identified using computational approaches based on genomic co-location within defence islands, but these screens may not be exhaustive. Here we developed an experimental selection scheme agnostic to genomic context to identify defence systems in 71 diverse E. coli strains. Our results unveil 21 conserved defence systems, none of which were previously detected as enriched in defence islands. Additionally, our work indicates that intact prophages and mobile genetic elements are primary reservoirs and distributors of defence systems in E. coli, with defence systems typically carried in specific locations or hotspots. These hotspots encode dozens of additional uncharacterized defence system candidates. Our findings reveal an extended landscape of antiviral immunity in E. coli and provide an approach for mapping defence systems in other species.
-    Sensor: Unknown
-    Activator: Unknown
-    Effector: Unknown
+contributors:
+    - Hugo Vaysset
+relevantAbstract:
+    - doi: 10.1038/s41564-022-01219-4
 ---
 
 # PD-T7-1
+
+## Description
+PD-T7-1 is a single gene defense systems which was discovered in :ref{doi=10.1038/s41564-022-01219-4}. Its antiphage activity was assessed in *E. coli* and it was shown to be active against T7.
+
+## Molecular mechanism
+As far as we are aware, the molecular mechanism is unknown.
+
 ## Example of genomic structure
 
 The PD-T7-1 system is composed of one protein: PD-T7-1.
@@ -23,7 +31,6 @@ Here is an example found in the RefSeq database:
 PD-T7-1 system in the genome of *Escherichia coli* (GCF_007833255.1) is composed of 1 protein: PD-T7-1 (WP_000008839.1).
 
 ## Distribution of the system among prokaryotes
-
 The PD-T7-1 system is present in a total of 136 different species.
 
 Among the 22k complete genomes of RefSeq, this system is present in 755 genomes (3.3 %).
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-## Relevant abstracts
-
-::relevant-abstracts
----
-items:
-    - doi: 10.1038/s41564-022-01219-4
-
----
-::