change AVAST to Avs

content/2.defense-systems/avast.md → content/2.defense-systems/avs.md

 ---
-title: AVAST
+title: Avs
 tableColumns:
     article:
       doi: 10.1126/science.aba0372
@@ -11,54 +11,54 @@ tableColumns:
 
 ---
 
-# AVAST
-# AVAST
+# Avs
+# Avs
 ## Description 
-AVAST (antiviral ATPases/NTPases of the STAND superfamily) is a group of anti-phage defense systems, active against some dsDNA phages. 
+Avs (antiviral ATPases/NTPases of the STAND superfamily) is a group of anti-phage defense systems, active against some dsDNA phages. 
 
-AVAST systems are composed of NTPases of the STAND (signal transduction ATPases with numerous associated domains) superfamily (1).  STAND-NTPases typically contain a C-terminal helical sensor domain that activates the N-terminal effector domain upon target recognition (1).
+Avs systems are composed of NTPases of the STAND (signal transduction ATPases with numerous associated domains) superfamily (1).  STAND-NTPases typically contain a C-terminal helical sensor domain that activates the N-terminal effector domain upon target recognition (1).
 
-In eukaryotes, STAND-NTPases are associated with programmed cell death, therefore Gao and colleagues hypothesized that AVAST might function through an Abortive infection mechanism.
+In eukaryotes, STAND-NTPases are associated with programmed cell death, therefore Gao and colleagues hypothesized that Avs might function through an Abortive infection mechanism.
 
 ## Example of genomic structure
 
-The AVAST system have been describe in a total of 5 subsystems.
+The Avs system have been describe in a total of 5 subsystems.
 
 Here is some example found in the RefSeq database:
 
-![avast](/avast/AVAST_I.svg){max-width=750px}
+![avs](/avs/Avs_I.svg){max-width=750px}
 
-AVAST_I subsystem in the genome of *Vibrio sp.* (GCF_905175355.1) is composed of 3 proteins: Avs1A (WP_208445041.1), Avs1B (WP_208445042.1)and, Avs1C (WP_108173272.1).
+Avs_I subsystem in the genome of *Vibrio sp.* (GCF_905175355.1) is composed of 3 proteins: Avs1A (WP_208445041.1), Avs1B (WP_208445042.1)and, Avs1C (WP_108173272.1).
 
-![avast](/avast/AVAST_II.svg){max-width=750px}
+![avs](/avs/Avs_II.svg){max-width=750px}
 
-AVAST_II subsystem in the genome of *Escherichia coli* (GCF_018884505.1) is composed of 1 protein: Avs2A (WP_032199984.1).
+Avs_II subsystem in the genome of *Escherichia coli* (GCF_018884505.1) is composed of 1 protein: Avs2A (WP_032199984.1).
 
-![avast](/avast/AVAST_III.svg){max-width=750px}
+![avs](/avs/Avs_III.svg){max-width=750px}
 
-AVAST_III subsystem in the genome of *Enterobacter cancerogenus* (GCF_002850575.1) is composed of 2 proteins: Avs3B (WP_199559884.1)and, Avs3A (WP_101737373.1).
+Avs_III subsystem in the genome of *Enterobacter cancerogenus* (GCF_002850575.1) is composed of 2 proteins: Avs3B (WP_199559884.1)and, Avs3A (WP_101737373.1).
 
-![avast](/avast/AVAST_IV.svg){max-width=750px}
+![avs](/avs/Avs_IV.svg){max-width=750px}
 
-AVAST_IV subsystem in the genome of *Escherichia coli* (GCF_016903595.1) is composed of 1 protein: Avs4A (WP_000240574.1).
+Avs_IV subsystem in the genome of *Escherichia coli* (GCF_016903595.1) is composed of 1 protein: Avs4A (WP_000240574.1).
 
-![avast](/avast/AVAST_V.svg){max-width=750px}
+![avs](/avs/Avs_V.svg){max-width=750px}
 
-AVAST_V subsystem in the genome of *Leclercia adecarboxylata* (GCF_006171285.1) is composed of 1 protein: Avs5A (WP_139565349.1).
+Avs_V subsystem in the genome of *Leclercia adecarboxylata* (GCF_006171285.1) is composed of 1 protein: Avs5A (WP_139565349.1).
 
 ## Distribution of the system among prokaryotes
 
-The AVAST system is present in a total of 363 different species.
+The Avs system is present in a total of 363 different species.
 
 Among the 22k complete genomes of RefSeq, this system is present in 1046 genomes (4.6 %).
 
-![avast](/avast/Distribution_AVAST.svg){max-width=750px}
+![avs](/avs/Distribution_Avs.svg){max-width=750px}
 
-*Proportion of genome encoding the AVAST system for the 14 phyla with more than 50 genomes in the RefSeq database.* *Pie chart of the repartition of all the subsystems found in the RefSeq database.*
+*Proportion of genome encoding the Avs system for the 14 phyla with more than 50 genomes in the RefSeq database.* *Pie chart of the repartition of all the subsystems found in the RefSeq database.*
 
 ## Experimental validation
 
-AVAST systems were experimentally validated using:
+Avs systems were experimentally validated using:
 
 Subsystem SIR2-STAND with a system from *Escherichia fergusonii's PICI (EfCIRHB19-C05)* in *Escherichia coli* has an anti-phage effect against T4, Lambda, HK97, HK544, HK578, T7 (Fillol-Salom et al., 2022)