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Commit 63bcba9d authored by ftesson's avatar ftesson
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add description, mechanism fix accession of the exp validated protein

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...@@ -12,7 +12,17 @@ relevantAbstracts: ...@@ -12,7 +12,17 @@ relevantAbstracts:
# FS_HsdR_like # FS_HsdR_like
## To do ## Description
FS_HsdR_like or HsdR_like was discovered in 2022 :ref{doi=10.1016/j.cell.2022.07.014} inside the PICI KpCIC51 in *Klebsiella pneumoniae*.
The HsdR_like system is also effective for blocking conjugation.
The HsdR_like system is composed of tree genes. A first protein encoding a DUF6731 domain and named after it. An hypothetical protein and the HsdR protein with an N terminal HEPN domain and C terminal Zn finger domain.
## Molecular mechanism
As far as we are aware, the molecular mechanism is unknown.
## Example of genomic structure ## Example of genomic structure
...@@ -66,7 +76,7 @@ dataUrls: ...@@ -66,7 +76,7 @@ dataUrls:
graph LR; graph LR;
Fillol-Salom_2022[<a href='https://doi.org/10.1016/j.cell.2022.07.014'>Fillol-Salom et al., 2022</a>] --> Origin_0 Fillol-Salom_2022[<a href='https://doi.org/10.1016/j.cell.2022.07.014'>Fillol-Salom et al., 2022</a>] --> Origin_0
Origin_0[Klebsiella pneumoniae Origin_0[Klebsiella pneumoniae
<a href='https://ncbi.nlm.nih.gov/protein/QFH39805.1'>QFH39805.1</a>, <a href='https://ncbi.nlm.nih.gov/protein/RXS01985.1'>RXS01985.1</a>] --> Expressed_0[Escherichia coli] <a href='https://ncbi.nlm.nih.gov/protein/QFH39804.1'>QFH39804.1</a>, <a href='https://ncbi.nlm.nih.gov/protein/QFH39805.1'>QFH39805.1, <a href='https://ncbi.nlm.nih.gov/protein/QFH39806.1'>QFH39806.1</a>] --> Expressed_0[Escherichia coli]
Expressed_0[Escherichia coli] ----> T5 & Lambda & HK97 & HK544 & HK544 & HK578 & T7 Expressed_0[Escherichia coli] ----> T5 & Lambda & HK97 & HK544 & HK544 & HK578 & T7
Fillol-Salom_2022[<a href='https://doi.org/10.1016/j.cell.2022.07.014'>Fillol-Salom et al., 2022</a>] --> Origin_0 Fillol-Salom_2022[<a href='https://doi.org/10.1016/j.cell.2022.07.014'>Fillol-Salom et al., 2022</a>] --> Origin_0
Origin_0[Klebsiella pneumoniae Origin_0[Klebsiella pneumoniae
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