Skip to content
Snippets Groups Projects
Commit 6b7ff6cb authored by aherrero's avatar aherrero
Browse files

Update eleos.md

parent e81bbfca
No related branches found
No related tags found
1 merge request!84Update eleos.md
Pipeline #116453 passed
......@@ -10,13 +10,28 @@ tableColumns:
Activator: Unknown
Effector: Unknown
PFAM: PF00350, PF01926, PF18709
contributors:
- Alba Herrero del Valle
## Relevant abstracts
::relevant-abstracts
---
items:
- doi: 10.1016/j.chom.2022.09.017
- doi: 10.1101/2022.12.12.520048
---
---
# Eleos
The Eleos system was previously described as the Dynamins-like system in (Millman et al, 2022).
## Description
The Eleos (for the greek goddess of mercy) system was previously described as the Dynamins-like system in by Millman et al. :ref{doi=10.1016/j.chom.2022.09.017}. It is formed by the LeoA and LeoBC proteins. LeoBC has been found to be analogous to GIMAPs (GTPases immunity-associated proteins), that are interferon inducible :ref{doi=10.1101/2022.12.12.520048}. LeoA in *E. coli* ETEC H10407 localises to the periplasm and has been suggested to potientiate bacterial virulence. Its crystal structure has been solved :ref{doi=10.1371/journal.pone.0107211}. Eleos from *Bacillus vietnamensis* NBRC 101237 has been found to protect against jumbo-phages in *Bacillus subtilis* :ref{doi=10.1016/j.chom.2022.09.017}.
## Molecular mechanism
As far as we are aware, the molecular mechanism is unknown.
## Example of genomic structure
The Eleos system is composed of 2 proteins: LeoA and, LeoBC. Sometimes, the systems is in three genes: LeoA, LeoB and LeoC.
The Eleos system is composed of 2 proteins: LeoA and, LeoBC. Sometimes, the system is in three genes: LeoA, LeoB and LeoC, or one gene LeoABC.
Here is an example found in the RefSeq database:
......@@ -77,13 +92,6 @@ end
style Title3 fill:none,stroke:none,stroke-width:none
style Title4 fill:none,stroke:none,stroke-width:none
</mermaid>
## Relevant abstracts
::relevant-abstracts
---
items:
- doi: 10.1016/j.chom.2022.09.017
---
::
0% Loading or .
You are about to add 0 people to the discussion. Proceed with caution.
Please register or to comment