AbiZ was discovered in 2006 on a *Lactococcus lactis* conjugative plasmid pTR2030 :ref{doi=10.1128/JB.00904-06}.
AbiZ is one of the so-called "Abi" systems for "Abortive infection" discovered in the 90's in research related to the dairy industry :ref{doi=10.1016/j.mib.2005.06.006}. AbiZ is classified as abortive infection in :ref{doi=10.1016/j.mib.2023.102312}.
AbiZ is composed of a single protein AbiZ.
## Molecular mechanism
AbiZ acts as an abortive infection system. AbiZ proteins sense holins and lysins from the infecting bacteriophage and use them to induce premature cell lysis :ref{doi=10.1128/JB.00904-06,10.1146/annurev-virology-011620-040628}.