PD-T7-1 is a single gene defense systems which was discovered in :ref{doi=10.1038/s41564-022-01219-4}. Its antiphage activity was assessed in *E. coli* and it was shown to be active against T7.
## Molecular mechanism
As far as we are aware, the molecular mechanism is unknown.
## Example of genomic structure
## Example of genomic structure
The PD-T7-1 is composed of 1 protein: PD-T7-1.
The PD-T7-1 is composed of 1 protein: PD-T7-1.
...
@@ -25,8 +34,12 @@ Here is an example found in the RefSeq database:
...
@@ -25,8 +34,12 @@ Here is an example found in the RefSeq database:
The PD-T7-1 system in *Klebsiella sp. P1927* (GCF_018204675.1, NZ_CP073377) is composed of 1 protein: PD-T7-1 (WP_004150873.1)
The PD-T7-1 system in *Klebsiella sp. P1927* (GCF_018204675.1, NZ_CP073377) is composed of 1 protein: PD-T7-1 (WP_004150873.1)
## Distribution of the system among prokaryotes
## Distribution of the system among prokaryotes
<<<<<<< content/3.defense-systems/pd-t7-1.md
The PD-T7-1 system is present in a total of 136 different species.
=======
Among the 22,803 complete genomes of RefSeq, the PD-T7-1 is detected in 748 genomes (3.28 %).
Among the 22,803 complete genomes of RefSeq, the PD-T7-1 is detected in 748 genomes (3.28 %).