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Commit 9204dab2 authored by Gemma C. Atkinson's avatar Gemma C. Atkinson Committed by ftesson
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Update rosmerta.md

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......@@ -24,11 +24,11 @@ The RosmerTA system was found to have antiviral activity and named after Gallo-R
## Molecular mechanisms
The RosmerTA system encodes a Zn-peptidase and a toxin of unknown function :ref{doi=10.1016/j.chom.2022.09.017} and was later found to induce membrane depolarization :ref{doi=10.1073/pnas.2305393120}.
The RosmerTA system encodes a Zn-peptidase and a toxin of unknown function :ref{doi=10.1016/j.chom.2022.09.017}. One toxin representative has been found to induce membrane depolarization :ref{doi=10.1073/pnas.2305393120}.
## Example of genomic structure
The RosmerTA is composed of 2 proteins: RmrT and RmrA.
The RosmerTA is composed of 2 proteins: RmrT and RmrA. The toxin can vary in sequence and structure.
Here is an example found in the RefSeq database:
......@@ -88,3 +88,27 @@ end
style Title3 fill:none,stroke:none,stroke-width:none
style Title4 fill:none,stroke:none,stroke-width:none
</mermaid>
<mermaid>
graph LR;
Ernits_2023[<a href='https://www.pnas.org/doi/10.1073/pnas.2305393120'>Ernits et al., 2023</a>] --> Origin_0
Origin_0[Gordonia phage Kita
<a href='https://www.ncbi.nlm.nih.gov/protein/YP_009301394.1/'>YP_009301394.1</a>, <a href='https://www.ncbi.nlm.nih.gov/protein/YP_009301394.1'>YP_009301394.1</a>] --> Expressed_0[Escherichia coli]
Expressed_0[Escherichia coli] ----> Bas54 and Bas59
subgraph Title1[Reference]
Ernits_2023
end
subgraph Title2[System origin]
Origin_0
end
subgraph Title3[Expression species]
Expressed_0
end
subgraph Title4[Phage infected]
Bas54
Bas59
end
style Title1 fill:none,stroke:none,stroke-width:none
style Title2 fill:none,stroke:none,stroke-width:none
style Title3 fill:none,stroke:none,stroke-width:none
style Title4 fill:none,stroke:none,stroke-width:none
</mermaid>
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