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Commit 9ea54fe8 authored by Jean  CURY's avatar Jean CURY
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Merge branch 'aherrero-main-patch-57551' into 'main'

Update sanata.md

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...@@ -10,9 +10,23 @@ tableColumns: ...@@ -10,9 +10,23 @@ tableColumns:
Activator: Unknown Activator: Unknown
Effector: Unknown Effector: Unknown
PFAM: PF08843 PFAM: PF08843
contributors:
- Alba Herrero del Valle
relevantAbstracts:
- doi: 10.1016/j.molcel.2013.02.002
--- ---
# SanaTA # SanaTA
## Description
The SanaTA system is composed of 2 proteins: SanaT and, SanaA, where SanaT encodes a toxin and SanaA encodes an antitoxin to form a toxin-antitoxin (TA) system. The toxin protein, SanaT, contains a Nucleotidyl transferase domain (PF08843). This system provides resistance against mutated T7 phages that lack the nonessential 4.5 gene in *Shewanella sp.* ANA-3. Sberro et al. showed that the defensiveness of sanaTA depends on the cleavage of SanaA by the Lon system, a protease that degrades the antitoxin to allow the activity of the toxin :ref{doi=10.1016/j.molcel.2013.02.002}.
## Molecular mechanism
It has been shown to function as a toxin-antitoxin (TA) system.
## Example of genomic structure ## Example of genomic structure
The SanaTA system is composed of 2 proteins: SanaT and, SanaA. The SanaTA system is composed of 2 proteins: SanaT and, SanaA.
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## Relevant abstracts
::relevant-abstracts
---
items:
- doi: 10.1016/j.molcel.2013.02.002
---
::
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