abio_hackaton

merge request related to issue #212 (closed)

content/3.defense-systems/abio.md

@@ -11,11 +11,26 @@ tableColumns:
     Effector: Unknown
     PFAM: PF01443, PF09848
 relevantAbstracts:
-    - doi: 10.1023/A:1002027321171
-    - doi: 10.1016/j.mib.2005.06.006
+  - doi: 10.1023/A:1002027321171
+  - doi: 10.1016/j.mib.2005.06.006
+  - doi: 10.3168/jds.S0022-0302(98)75713-3
 ---
 
 # AbiO
+
+## Description
+
+AbiO is a single gene defense system discovered in 1998 :ref{doi=10.3168/jds.S0022-0302(98)75713-3}.
+
+AbiO is one of the so-called "Abi" systems for "Abortive infection" discovered in the 90's in research related to the dairy industry :ref{doi=10.1016/j.mib.2005.06.006}. Even though, their name correspond to abortive infection, their mechanism of action does not necessarily correspond to an abortive infection. AbiO is classified as possible Abortive infection in :ref{doi=10.1016/j.mib.2023.102312}.
+
+
+This system is only composed of one single gene containing a helicase domain.
+
+## Molecular mechanism
+
+As far as we are aware, the molecular mechanism is unknown.
+
 ## Example of genomic structure
 
 The AbiO is composed of 1 protein: AbiO.
@@ -55,12 +70,12 @@ dataUrls:
 
 <mermaid>
 graph LR;
-    Chopin_2005[<a href='https://doi.org/10.1016/j.mib.2005.06.006'>Chopin et al., 2005</a>] --> Origin_0
+    Prevots_1998[<a href='https://doi.org/10.3168/jds.S0022-0302(98)75713-3'>Prevots et al., 1998</a>] --> Origin_0
     Origin_0[lactococcal plasmid  
-<a href='https://ncbi.nlm.nih.gov/protein/insideplasmid:I61427.1'>insideplasmid:I61427.1</a>] --> Expressed_0[lactococci]
+<a href='https://ncbi.nlm.nih.gov/protein/I61427.1'>In the plasmid : I61427.1</a>] --> Expressed_0[lactococci]
     Expressed_0[lactococci] ----> 936 & c2
     subgraph Title1[Reference]
-        Chopin_2005
+        Prevots_1998
 end
     subgraph Title2[System origin]
         Origin_0
@@ -78,3 +93,5 @@ end
     style Title4 fill:none,stroke:none,stroke-width:none
 </mermaid>
 
+
+