p("The Pv SeroTAT Tool has been developed by Ivo Mueller's research groups at the Institut Pasteur and Walter and Eliza Hall Institut of Medical Research. The tool is a patented diagnostic test based on validated serological markers of recent",tags$em("Plasmodium vivax")," infections and hypnozoite carriage. The tool uses machine learning classification algorithms (Random Forest (RF) and Support Vector Machine (SVM)) to predict sero-positivity with varying performance."),
p("Validation of this tool using Random Forest can be found in the",a("Nature Medicine Publication",href="https://www.nature.com/articles/s41591-020-0841-4")),
p("Please contact on how to cite this tool in publications."),
p(em("Follow steps 1 - 6 to process Luminex MFI or Relative Antibody Unit (RAU) data and run the diagnostic test.")),
p(em("Follow steps 1 - 6 to process Luminex/BioPlex MFI or Relative Antibody Unit (RAU) data and run the diagnostic test.")),
hr()),
tabPanel("Biomarkers of exposure",
br(),
...
...
@@ -216,7 +216,7 @@ ui <- fluidPage(
fileInput("MFI_file",
h5("4.1 Load raw MFI file (required)"),
accept=c(".csv",".xlsx")),
helpText("Note: a (.csv) or (.xlsx) file of raw outputs of the Luminex-MagPix machine.
helpText("Note: a (.csv) or (.xlsx) file of raw outputs of the Luminex-MagPix or BioPlex machine.
If you encounter errors when loading a (.csv) file, convert it to (.xlsx) in Excel and load the (.xlsx) file instead.")),