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Commit 96da995b authored by hvaysset's avatar hvaysset Committed by ftesson
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Update pd-t7-5.md

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Sensor: Unknown
Activator: Unknown
Effector: Unknown
contributors:
- Hugo Vaysset
relevantAbstracts:
- doi: 10.1038/s41564-022-01219-4
- doi: 10.1038/s41564-022-01219-4
---
# PD-T7-5
## Example of genomic structure
The PD-T7-5 is composed of 1 protein: PD-T7-5.
## Description
PD-T7-5 is a defense system composed of a single protein which was discovered in :ref{doi=10.1038/s41564-022-01219-4}. Its antiphage activity was assessed by heterologous expression in *E. coli* against T7 and to reduce the size of lysis plaques of T3 :ref{doi=10.1038/s41564-022-01219-4}. PD-T7-5 contains a PD(D/E)XK nuclease domain like [PD-T7-1](/defense-systems/pd-t7-1).
## Molecular mechanism
As far as we are aware, the molecular mechanism is unknown. However, the presence of a PD(D/E)XK domain in PD-T7-5 suggests a mechanism of action via DNA degradation :ref{doi=10.1038/s41564-022-01219-4}.
## Example of genomic structure
The PD-T7-5 system is composed of one protein: PD-T7-5.
Here is an example found in the RefSeq database:
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